The Silent Struggle: 11 Challenges Facing Community Pharmacies—and How to Overcome Them
- RxConnexion
- Apr 29
- 3 min read
The Silent Struggle: 11 Challenges Facing Community Pharmacies—and How to Overcome Them
Independent community pharmacies are the backbone of local healthcare—offering personalized service, trusted relationships, and vital access to medications. Yet behind the counter, many owners face an uphill battle against industry consolidation, shrinking margins, and operational hurdles.
Below are 11 major challenges that community pharmacies face today—along with practical, forward-thinking strategies to overcome them.
1. Low Negotiation Power with PBMs and Wholesalers
The Challenge:
Independent pharmacies often lack the volume to negotiate competitive reimbursement rates or favorable drug pricing.
The Solution:
Join a Pharmacy Services Administrative Organization (PSAO) or purchasing cooperative that can aggregate buying power. Consider transitioning to a cash-based or hybrid pricing model, like CostPlusRx, that bypasses PBMs entirely.
2. Difficult to Grow in a Competitive Market
The Challenge:
It’s hard to scale when up against national chains with massive advertising budgets.
The Solution:
Differentiate with niche clinical services (e.g., weight loss, hormone therapy, travel vaccines). Use digital tools and telemedicine to expand your service footprint—without needing a new physical location.
3. Competing Against Scaled Players (PE-Backed Chains & Health Systems)
The Challenge:
Private equity and hospital-owned pharmacies can undercut pricing and operate at a loss to gain market share.
The Solution:
Lean into what they can’t offer—high-touch care, flexible service offerings, and a local reputation. Bundle value-added services with fulfillment to retain patients and attract new ones.
4. Rising Administrative Burdens
The Challenge:
DIR fees, audits, and compliance documentation eat into already-tight margins.
The Solution:
Automate repetitive tasks with pharmacy management systems, claim reconciliation software, and AI-driven documentation tools. Outsource billing or compliance tracking to trusted partners when possible.
5. Costly and Challenging Staff Recruitment
The Challenge:
Finding reliable pharmacists and techs—especially in rural or underserved areas—is difficult and expensive.
The Solution:
Offer flexible work schedules, professional development opportunities, and remote staffing models (e.g., telepharmacy or virtual intake staff). Use targeted job boards and pharmacy-specific recruiting platforms.
6. Limited Interest from Younger Pharmacists
The Challenge:
Many new graduates prefer the stability and benefits of chain pharmacies or hospital systems.
The Solution:
Create ownership paths or profit-sharing plans to attract entrepreneurial pharmacists. Emphasize autonomy, community impact, and growth potential through services and technology.
7. High IT & Compliance Costs, With Little Support
The Challenge:
Staying compliant with HIPAA, state boards, and cybersecurity requirements is both costly and complex.
The Solution:
Partner with specialized pharmacy IT vendors that offer bundled services, HIPAA-compliant platforms, and 24/7 support. Look for turnkey solutions that combine EHR, CRM, and patient engagement tools under one umbrella.
8. Limited Marketing Resources
The Challenge:
Most pharmacies lack the budget or in-house expertise for marketing.
The Solution:
Use affordable digital strategies—like social media, email newsletters, and SEO-optimized websites—to amplify your reach. Leverage white-labeled marketing programs built specifically for pharmacies.
9. No Investment in Growth
The Challenge:
Many pharmacies are stuck in a reactive mode—focused on survival rather than innovation.
The Solution:
Dedicate even 2-5% of revenue to growth initiatives. Start small with pilot programs—like telehealth or supplement sales—and track ROI closely to reinvest wisely.
10. No Economies of Scale
The Challenge:
Higher per-unit costs and inefficiencies impact profitability.
The Solution:
Leverage technology to scale smartly—whether through automation, centralized services, or multi-store alliances. Consider merging operations or collaborating on purchasing, marketing, or clinical services.
11. Lack of Exit Plan Near Retirement
The Challenge:
Many owners nearing retirement don’t have a clear succession or sale strategy.
The Solution:
Start planning early. Build value in your business by diversifying revenue, systematizing operations, and improving profitability. Explore sale, partnership, or internal buyout options—and document everything.
Community pharmacies are under pressure—but they’re not powerless. By adopting smarter tools, strategic partnerships, and a proactive mindset, pharmacy owners can not only survive—but thrive in a rapidly changing landscape.
If you’re ready to explore scalable solutions, schedule a discovery call with the team at RxConnexion. We’ll show you how to turn today’s challenges into tomorrow’s opportunities.

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